Effect of soya beans supplement on blood glucose levels and haematological indices on alloxan induced diabetic wistar rats

The aim of this study is to evaluate the effects of soya bean supplement blood glucose levels and haematological parameters on alloxan-induced diabetes in Wistar rats. The animals were grouped into four groups of five rats in each group. Diabetes was induced by single intraperitoneal injection of Alloxan monohydrate at a dose of 150mg/kg body weight. The animals were fed with 25% and 50% of the soya beans supplement for two weeks. Glibenclamide was used as a standard anti-diabetic drug and was given orally to the positive control diabetic group. The fasting blood glucose levels were determined at intervals of 0, 1, 3, 6, 9 and 12 days respectively. The animals were sacrificed and blood samples were taken from all the groups for the determination of haematological parameters. As regard to the blood glucose levels there was a significant decrease (p<0.05) when compared with the control non supplemented group. The highest activity resides at the group supplemented with 25% soya beans. In relation to the haematological parameters there was a significant increase in the white blood cell count, while packed cell volume, Red blood cell count diferential count and haemoglobin level there was no significant different between the control and soya beans supplemented groups.